A second understanding various types of tumor markers and their clinical significance – Sohu health-9c8996

A second read: all kinds of tumor markers and clinical significance of health health Sohu – Sohu sources said this time now online tumor tumor markers (tumor, marker, TM) is quite much, what the significance that apply to what tumor, the bullet went through the king speak generally, the literature summarizes tumor markers and hope to help readers. The old picture of a textbook, or a question. So, the ideal TM should be what kind of? Should have the following 6 points: 1: high sensitivity for early detection and early diagnosis; 2 high specificity: only positive tumor patients and other diseases are negative, can distinguish benign and malignant tumors; 3 positioning: organ specific, through the TM know this is a lung cancer or breast cancer; 4 severity evaluation the positive rate of TM and the concentration of tumor progression, know the size and severity; 5 monitoring therapeutic effect: efficacy and recurrence of tumor therapy; prognosis: 6 the TM know the prognosis is good. Common and common tumor serum TM CEA (carcinoembryonic antigen) is a kind of hollow organ, and the specificity of lung adenocarcinoma is strong. Ng mL (not less than 3 of normal smoking) less than 10 ng ml (smoking), more than 20 ng mL suggesting that the digestive tumor. It is a marker of tumor metastasis and recurrence. SCC (squamous cell carcinoma antigen) with its name, the specificity of cervical cancer squamous cell carcinoma; TM. CA125 (carbohydrate antigen 125) ovarian TM, independent prognosis of lung cancer TM; normal < 35 u mL. TM is the first choice of CA153 in breast cancer, and it increases with the increase of tumor stage. The normal range is 28 ng mL. CA199 was the most sensitive source of pancreatic cancer (70%), followed by colorectal cancer (45%) and hepatocellular carcinoma (30%). Normal < 37 mL U. CA242 digestive source. NSE (neuron specific enolase) small cell lung cancer TM, glioma TM; neuroendocrine origin, is a signal of brain metastasis. TPA (tissue polypeptide antigen) reflects activity, differentiation and invasion. Lung cancer serum TM CYFRA21-1 (cytokeratin 21-1 fragment) lung squamous cell carcinoma is preferred TM, sensitivity 76.5%, non-small cell lung cancer specificity of 87%. Gastrin releasing peptide precursor (ProGRP) small cell lung cancer TM, sensitivity and specificity are good. Early detection can be used for screening high-risk patients with small cell lung cancer in Japan has been incorporated into the routine physical examination project. The positive rate of p53 tumor suppressor gene p53 was associated with the survival of patients with squamous cell carcinoma of the lung. Specific application of lung adenocarcinoma: CEA (87%), CA153 lung squamous cell carcinoma: SCC, CYFRA21-1 small cell lung cancer: pr.相关的主题文章: